PRESENTER: Amy Heffelfinger, Ph.D., ABPP-CN
PRESENTER BIO: Many factors influence brain development and functions including genetic makeup, family structure, socioeconomic well-being, and educational opportunities in addition to neurological or medical disorders. Dr. Heffelfinger hopes to get involved early in life to help the family understand how to optimize the child’s development. While basic cognitive abilities are very important, and at the core of a neuropsychological evaluation, Dr. Heffelfinger tries to also help families understand how to help their children function best at home, in school, socially, and in their community. Dr. Heffelfinger enjoys working with children starting at a young age and then helping them throughout their childhood and transitioning them into early adulthood. Dr. Amy Heffelfinger, a clinical neuropsychologist and Professor of Neurology, Neurosurgery, and Pediatrics has been at the Medical College of Wisconsin for 18 years. Dr. Heffelfinger specializes in the evaluation and treatment of preschool and school-age children with neurological, behavioral, and developmental disorders. Dr. Heffelfinger's current research involves the study of early development of neuropsychological function, with a focus on psychosocial impact. Dr. Heffelfinger is also very committed to education and mentoring. She has served as the Training Director at the Medical College of Wisconsin since 2008, recently finished her term as the Chair of the Medical College of Wisconsin’s Faculty Career Development Committee, and is currently the President of the Association for Postdoctoral Programs in Clinical Neuropsychology.
TITLE: Preschool Neuropsychological Development, Assessment, and Cultural Considerations
ABSTRACT: The neural systems underlying neuropsychological functions develop prenatally, throughout childhood, and into adulthood. The preschool period is both a time of rapid development and vulnerability. In the first years of life many neurological, medical, and genetic disorders onset, psychosocial and environmental stressors are hugely impactful, and positive relationships, education and interventions can influence neural system development. This talk will update the participants on neuropsychological development in the preschool years. The second half will describe procedures and interpretation techniques for conducting preschool assessments. Throughout, discussion will include cultural, family, psychosocial and ethical factors that influence development as well as considerations for testing.
PRESENTER: Melissa Lamar, Ph.D.
PRESENTER BIO: Dr. Melissa Lamar is a Cognitive Neuroscientist in the Rush Alzheimer’s Disease Center and an Associate Professor in the Department of Behavioral Sciences at the Rush University Medical Center. She also maintains a faculty affiliation within the Institute for Minority Health Research at the University of Illinois at Chicago and is a licensed Clinical Neuropsychologist. Dr. Lamar’s work is aimed towards the identification of preclinical markers of risk for and development of pathological aging and dementia in mid- to late-life older adults from a variety of racial, ethnic, and socioeconomic backgrounds. Her research has been supported by the NIH throughout her career, with her most recent grants focused on identifying modifiable factors underlying health disparities in brain aging. Dr. Lamar is also co-Investigator of the Hispanic Community Health Study/Study of Latinos (HCHS/SOL), the largest epidemiological study of cardiovascular disease risk factors in Hispanics and Latinos in the US to date. She is also a Chicago site PI of both the cognitive and neuroimaging ancillary studies of SOL. Dr. Lamar has over 85 peer-reviewed publications and proudly mentors several graduate and post-doctoral researchers. She was awarded the 2017 Arthur Benton Mid-Career Award from the International Neuropsychological Society and Fellow status within the Society for Clinical Neuropsychology and the American Psychological Association in 2016.
TITLE: Bridging science and humanity in search for modifiable markers of aging and dementia
ABSTRACT: Recent reports suggest declines in the age-specific risk of Alzheimer’s disease (AD) in higher-income Western countries. Despite this, investigators believe that worldwide trends of increasing mid-life modifiable risk factors (e.g., vascular risk factors), coupled with the growth of the world’s oldest age groups may nonetheless lead to an increase in dementia risk. Thus, the need for pre-clinical markers of AD and related dementias, and a greater understanding of modifiable factors associated with such markers, must continue if we are to successfully combat pathological aging. This CE course will take a ‘neurons to neighborhood’ approach to addressing these issues given that where people live, as well as how people live, impacts their experience and expression of brain-behavior profiles.
Beginning with an overview of early predictors of pathological brain aging to more recent developments in neuroimaging signatures of disease, this CE course will outline the implications of mixed pathologies associated with dementia including AD and vascular dementia (VaD) as a means to inform the search for preclinical markers in asymptomatic individuals. From there, cognitive phenotypes associated with these neuroimaging markers in preclinical samples, as well as lifestyle and community-based, i.e., neighborhood associates will be discussed.
Attendees of this workshop will come away with 1) an appreciation for the changing demographics of aging and dementia globally, 2) findings to date regarding neuroimaging markers of preclinical stages of disease, as well as the cognitive associates to these markers, and 3) a greater understanding of the role of individual lifestyle and community-based factors on these brain-behavior relationships. Given that the world is both ‘thoroughly globalized as well as startlingly unequal’ (Isaac Chotiner, Slate Magazine), it is the goal of this workshop to provide a springboard for discussions regarding future research investigating modifiable individual and/or community-based factors as intervention targets to ensure successful aging across diverse populations.
PRESENTERS: Ivan Rektor, MD and Bruce Hermann, PhD
PRESENTER BIOs: Ivan Rektor, MD, is a Professor at Masaryk University, Professor in the Department of Neurology at St. Anne’s Hospital and School of Medicine, and at the Central European Institute of Technology. He is also Head of the Centre of Neuroscience and a Co-ordinator of Brain and Mind Research Programmme. Lastly, he is the Research Group Leader for Multimodal and Functional Imaging. Bruce Hermann is a Professor and Director of the Matthews Neuropsychology Section in the Department of Neurology at the University of Wisconsin School of Medicine and Public Health. His clinical and research career has been devoted to understanding the effects of epilepsy and epilepsy surgery on cognition and behavior in children and adults.
TITLE: Advances in epilepsy treatment and understanding of neurobehavioral comorbidities.
ABSTRACT: The course will first overview issues pertinent to the treatment of drug-resistant epilepsies beginning with discussion of the major indications for epilepsy surgery and the relevant preoperative investigations including ictal video-EEG, advanced MRI, metabolic techniques (e.g., PET, ictal and interictal SPECT) and neuropsychological assessment. Interventions meant to be curative will be reviewed (e.g., lesionectomy, amydalo-hippocampectomy, topectomy, cortectomy, lobectomy, multilobar resection, hemispherectomy) as well as palliative methods (e.g., vagal nerve stimulation, deep brain stimulation [anterior nucleus of thalamus, centrum medianum thalami], responsive brain stimulation (cortex)). Other interventions, currently under active development and investigation, including radiosurgery and thermolesioning using inserted depth electrodes will be discussed. Intracerebral targets for chronic electrical stimulation under investigation will be reviewed as well as non-invasive brain stimulation techniques and the outcomes for these interventions. The course will then turn to the neurobehavioral comorbidities of the epilepsies including anomalies in cognition, behavior, and brain structure and their interrelationships. The emphasis will be on the natural history of these complications of epilepsy in children and adults taking a lifespan perspective with emphasis on the status of patients at the time of diagnosis and prospective change over time.